Diabetic Foot Disease (DFD)


Diabetic Foot Disease encompasses infection, ulceration, and osseous destruction of the foot of a person with diabetes, usually accompanied by neuropathy and/or PAD (Peripheral Arterial Disease) in the lower extremity. According to the International Diabetes Federation, it is predicted that adults (20-79 years) diagnosed with diabetes will rise to 643 million by 2030 from 537 million in 2021. As mentioned in the article “Update on prevention of diabetic foot ulcer” by Cesare Miranda et al., it was estimated that up to 34% of type 2 diabetes patients may develop diabetic foot ulcers once in their lifetime, and the risk for ulcer recurrence is high, with recurrence rates of 40% in the first year and 65% in the first 3 years after healing. The burden of diabetic foot disease is ranked in the top 10 of all medical conditions. Coming to the anatomy, ulceration in the neuropathic foot develops on the plantar surface, which is usually the location of high mechanical pressure. In contrast, ulcers in the foot with ischemia occur on the margins of the foot and tips of the toes, at sites of persistent low pressure usually from badly fitting shoes.

Capture Meditech’s Suction Assisted Closure (SAC) – Negative Pressure Wound Therapy (NPWT) can be effective across various grades of diabetic foot ulcers, but it’s typically more commonly used in moderate to severe cases, typically grades 3 and 4, as they are deeper wounds with potential infection and tissue damage. NPWT helps in several ways, including promoting wound healing, reducing edema, and controlling infection, which are particularly beneficial in more severe cases where traditional wound care methods may not be as effective. The decision to use NPWT should be made on a case-by-case basis by healthcare professionals considering factors such as wound characteristics, patient comorbidities, and treatment goals.” The infographic provided below illustrates the various Wagner grades of diabetic foot ulcers, accompanied by descriptions and images to enhance comprehension, highlighting the anatomical areas and depth of the ulcer, enabling the surgeon to interpret where SAC-NPWT can be effectively applied.


Meloni M, Izzo V, Vainieri E, Giurato L, Ruotolo V, Uccioli L. Management of negative pressure wound therapy in the treatment of diabetic foot ulcers. World J Orthop. 2015 May 18;6(4):387-93. doi: 10.5312/wjo.v6.i4.387. PMID: 25992316; PMCID: PMC4436907.

Miranda C, Da Ros R, Marfella R. Update on prevention of diabetic foot ulcer. Arch Med Sci Atheroscler Dis. 2021 Jun 30;6:e123-e131. doi: 10.5114/amsad.2021.107817. PMID: 34381913; PMCID: PMC8336435.

Welcome to IDF | International Diabetes Federation

Edmonds M, Manu C, Vas P. The current burden of diabetic foot disease. J Clin Orthop Trauma. 2021 Feb 8;17:88-93. doi: 10.1016/j.jcot.2021.01.017. PMID: 33680841; PMCID: PMC7919962.

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